Professor
Prof. Hassan Abdu Sagir Madkhali
علم الأدوية Pharmacy AL-Kharj - Pharmacology20Published research
Overview
Prof. Hassan Abdu Sagir Madkhali Faculty member in the field of علم الأدوية College Pharmacy AL-Kharj At Prince Sattam bin Abdulaziz University, he contributes to supporting the educational and learning process by offering academic courses, participating in educational activities and programs, and supporting the development of students' skills and enhancing their knowledge in the field. علم الأدوية
Academic qualifications
PhD in Pharmaceutical Sciences
Pharmacology - pharmacology
Mississippi State University — United States
2014
Bachelor Of Pharmacy
Pharmacy - pharmacy
King Saud University — Saudi Arabia
2008
Academic progression
Professor
علم الادوية - كلية الصيدلة بالخرج
2026
Associate Professor
علم الادوية - كلية الصيدلة بالخرج
2021
Assistant Professor
علم الادوية - كلية الصيدلة بالخرج
2015
Research interests
My research is focused on the physiological role of plasma kallikrein kinin system (KKS), coagulation system, Prolylcarboxypeptidase (PRCP), and their applications to human health and disease. I am also interested in screening natural products for drug discovery (anti-inflammatory, anti-obesity, anti-coagulant, and anti-thrombotic).
Published research
View all research (20)2026
Synthesis and in silico evaluation of novel hybrid 1,4-benzothiazine-1,1-dioxide–bis(1,2,3-triazole) derivatives as potential SRC kinase inhibitors via 1,3-dipolar cycloaddition
Computational Biology and Chemistry
Synthesis and in silico evaluation of novel hybrid 1,4-benzothiazine-1,1-dioxide–bis(1,2,3-triazole) derivatives as potential SRC kinase inhibitors via 1,3-dipolar cycloaddition
Computational Biology and Chemistry
Characterization of Platelet Protein Alterations in Stored Platelet Concentrates
journal of clinical medicine
Exploring the Association of Genetic Determinants of SIRT1, MTHFR, and MIR146A Gene Polymorphism with the Ischemic Stroke Predisposition: A Case Control Study
Cellular and Molecular Neurobiology
Design, synthesis and computational evaluation of 1, 2, 3-triazole-Schiff base hybrid as AKT1 inhibitor for breast cancer
chemical physics impact
Clinical exome sequencing identifies novel gene variants associated with ischemic stroke in the Saudi Tabuk population
FRONTIERS MEDIA SA
Diosmin as a Multitarget Therapeutic for Hydrocephalus: Insights from Network Pharmacology, Docking, and MD Simulation
SPRINGER
Discovery of Natural-product Chemotypes with Dual GSK-3?/HDAC6 Binding Potential via Receptor-guided Pharmacophore Screening, Molecular Docking and Dynamics Simulations
WORLD SCIENTIFIC PUBL CO PTE LTD
2025
Inhibition of Activated Coagulation Factor XII by the Phosphodiesterase-4 Inhibitor Roflumilast: In Vitro and In Silico Studies
Frontiers in Bioscience-Landmark
Myricetin alleviates indomethacin-induced gastric ulcers in rats via antioxidant, anti-inflammatory and antiapoptotic mechanisms
SPRINGER BASEL AG
Tailoring dual antiplatelet therapy for stroke prevention: a meta-analysis of timing, duration, regimen, and stroke subtypes
FRONTIERS MEDIA SA
Chloroform Extraction, Phytochemical Screening, GC-HRMS Analysis and Computational Investigation of Ehretia Laevis Roxb. as Potential MELK Inhibitor for the Treatment of Cancer
SAMI PUBLISHING CO-SPC
2018
Naringenin (4,5,7-trihydroxyflavanone) suppresses the development of precancerous lesions via controlling hyperproliferation and inflammation in the colon of Wistar rats
WILEY
Evaluation of the diuretic potentials of naringenin in hypercholesterolemic rats
PHARMACOTHERAPY GROUP
2019
Neuroprotective Strategies for Neurological Disorders by Natural Products: An update
BENTHAM SCIENCE PUBL LTD
Moringa oleifera Lam. (family Moringaceae) leaf extract attenuates high-fat diet-induced dyslipidemia and vascular endothelium dysfunction in Wistar albino rats
PHARMACOTHERAPY GROUP
Zingerone (4-(4-hydroxy-3-methylphenyl)butan-2-one) ameliorates renal function via controlling oxidative burst and inflammation in experimental diabetic nephropathy
TAYLOR & FRANCIS LTD
2020
Cadmium-induced Hepatotoxicity and Oxidative Stress in Rats: Protection by Roflumilast via NF-?B and HO-1 Pathway
ASIAN NETWORK SCIENTIFIC INFORMATION-ANSINET
Morin attenuates high-fat diet induced-obesity related vascular endothelial dysfunction in Wistar albino rats
ELSEVIER
2021
Red Yeast Rice Mitigates High-Fat Diet Induced-Obesity Related Vascular Dysfunction in Wistar Albino Rats
AMG TRANSCEND ASSOC
Courses
8 Decisions| Course code | Course Name |
|---|---|
| PHL 319 | Pharmacology-1 |
| PHL 419 | Pharmacology-4 |
| PHL 218 | Anatomy and Physiology-1 |
| PHL 329 | Pharmacology-3 |
| PHL 328 | Pharmacology-2 |
| PHL 439 | Toxicology |
| PHL 227 | Anatomy and Physiology-2 |
| PHTR 495 | Research Project |
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